Seed Proposal Spotlight:
Single Molecule Detection in Living Cells and Tissues Using a New Class of Optical Sensors Based on Single Walled Carbon Nanotubes

Michael S. Strano
Department of Chemical and Biomolecular Engineering
Taekjip Ha
Department of Physics
Thomas Eurell
Department of Veterninary Sciences
Klaus J. Schulten
Departments of Physics & Chemistry
Ilesanmi Adesida
Department of Electrical and Computing Engineering
Bibiania Onoa
Dupont Research
The focus of this research is to develop the scientific and engineering basis necessary to realize robust, single molecule detection in living cells in real time. The outcome could lead to technologies that transform science and medicine by creating probes as small as a single molecule that could communicate information about the sub-cellular environment remotely using near infrared light. This would have immediate applications to single cell physiometry, metabolic pathway engineering, disease diagnostics and biomarker identification, cell signaling and tracking trace analytes. {More on the Seed Proposals}